OCT4 antibody
Quick Overview for OCT4 antibody (ABIN781220)
Target
See all OCT4 (POU5F1) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Specificity
- Nucleus
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Purification
- Protein G-Sepharose affinity purified
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Immunogen
- Recombinant full length of Mouse POU5F1.
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Isotype
- IgG
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Application Notes
- Recommended dilutions. ELISA: 1/5000 - 1/20000. WB: 1/100-1/2000.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 50µg/50µl
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Buffer
- 0.02% Sodium Azide, 50% glycerol, 1% BSA, PBS, pH7.4.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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- OCT4 (POU5F1) (POU Class 5 Homeobox 1 (POU5F1))
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Alternative Name
- POU5F1
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Background
- POU5F1(Oct-4) is a transcription factor highly expressed in undifferentiated embryonic stem cells and embryonic germ cells. A network of key factors that includes Oct-4, Nanog, and Sox2 is necessary for the maintenance of pluripotent potential, and downregulation of Oct-4 has been shown to trigger cell differentiation. Oct-4 is a useful germ cell tumor marker. Oct-4 exists as two splice variants, Oct-4A and Oct-4B.
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Molecular Weight
- 45kDa
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NCBI Accession
- NM_013633
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Pathways
- Stem Cell Maintenance
Target
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